Enalaprilat
Enalaprilat is the active metabolite of enalapril and belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby promoting blood vessel relaxation and lowering blood pressure. This medication is primarily used for the management of hypertension when rapid blood pressure reduction is needed.
Enalaprilat is an ACE inhibitor that lowers blood pressure by blocking the formation of angiotensin II, a hormone that constricts blood vessels.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- RxNorm
- 3829
- Generic
- Enalaprilat
- Class
- unclassified
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of hypertension when rapid or controlled onset of action is needed. Often used in hospital settings when oral medication is not feasible.
Enalaprilat inhibits angiotensin-converting enzyme (ACE), preventing the conversion of angiotensin I to angiotensin II. This reduces vasoconstriction and decreases aldosterone secretion, resulting in lower blood pressure and reduced cardiac workload.
Administered intravenously. Monitor blood pressure and renal function during treatment. Contraindicated in patients with angioedema history or bilateral renal artery stenosis. May cause hypotension, especially in volume-depleted patients. Avoid during pregnancy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy