Niacin
Endur-Acin is a brand-name extended-release formulation of niacin (vitamin B3) used to treat and prevent pellagra, a condition caused by niacin deficiency. It is also commonly prescribed to help improve cholesterol profiles by raising HDL (good) cholesterol and lowering LDL (bad) cholesterol and triglycerides. As a sustained-release product, it is designed to provide steady niacin levels over time, which may help reduce flushing side effects compared to immediate-release formulations.
Endur-Acin is an extended-release niacin (vitamin B3) supplement used to treat niacin deficiency and improve cholesterol levels.
Key facts at a glance
- RxNorm
- 1088776
- Generic
- Endur-Acin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Endur-Acin is primarily used to treat and prevent pellagra (niacin deficiency), which causes symptoms like dermatitis, diarrhea, and dementia. It is also frequently prescribed off-label to help manage dyslipidemia, particularly for raising HDL cholesterol, lowering LDL cholesterol, and reducing triglyceride levels.
As a form of vitamin B3, niacin functions as a component of coenzymes involved in cellular energy metabolism. In lipid management, it helps reduce the liver's production of LDL cholesterol and triglycerides while inhibiting the breakdown of HDL cholesterol, leading to improved overall lipid profiles.
Common side effects include flushing, warmth, and redness (especially of the face), as well as potential stomach upset. Patients with liver disease, active peptic ulcers, or severe hypotension should use this medication with caution. Extended-release formulations like Endur-Acin should not be crushed or chewed. Regular monitoring of liver function and lipid panels is typically recommended during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy