Hepatitis B Vaccine
Engerix-B is a recombinant hepatitis B vaccine used to prevent hepatitis B virus infection. It is approved for use in individuals of all ages, from infants to adults, and is typically administered in a series of doses for optimal protection. The vaccine is recommended for people at risk of hepatitis B exposure, including healthcare workers, travelers to endemic regions, and those with certain health conditions.
Engerix-B is a brand-name hepatitis B vaccine that provides protection against hepatitis B virus infection.
Key facts at a glance
- RxNorm
- 49610
- Generic
- Engerix-B
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Engerix-B is indicated for active immunization against hepatitis B virus infection in individuals of all ages. It is recommended for neonates, children, adolescents, and adults, particularly those at increased risk of hepatitis B exposure such as healthcare workers, people with multiple sexual partners, individuals with chronic liver disease, and those traveling to regions with high hepatitis B endemicity.
Engerix-B is a recombinant DNA vaccine that contains the hepatitis B surface antigen (HBsAg) produced in yeast cells. The vaccine stimulates the immune system to produce protective antibodies against the hepatitis B virus without causing the actual disease. This active immunization helps the body develop immunity to future hepatitis B virus exposure.
Engerix-B is contraindicated in individuals with known hypersensitivity to any component of the vaccine. Common side effects may include soreness at the injection site, headache, and fatigue. The vaccine is administered intramuscularly and typically requires multiple doses over a 6-month period to achieve full protection. Vaccination does not eliminate the need for standard precautions to prevent hepatitis B transmission.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy