Alofisel
Enjaymo (sutimlimab) is a monoclonal antibody indicated for the treatment of hemolysis in adults with cold agglutinin disease (CAD). It works by inhibiting the classical complement pathway, thereby reducing the destruction of red blood cells. This medication is administered via intravenous infusion.
Enjaymo is a monoclonal antibody used to treat cold agglutinin disease by inhibiting complement-mediated red blood cell destruction.
Key facts at a glance
- RxNorm
- 2591421
- Generic
- Enjaymo
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of hemolysis in adults with cold agglutinin disease (CAD), a rare autoimmune disorder where antibodies attack red blood cells in cold temperatures.
Enjaymo is a humanized monoclonal antibody that targets and inhibits C1s, a protein in the classical complement pathway, thereby preventing complement-mediated destruction of red blood cells.
Administered as an intravenous infusion. Patients should be monitored for infections, as complement inhibition may increase susceptibility. Not indicated for acute hemolytic crisis. May interact with other complement inhibitors or vaccines.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy