Entecavir
Entecavir is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults and children. It works by inhibiting the HBV DNA polymerase enzyme, which is essential for the virus to replicate and multiply in the body. This medication helps reduce the amount of virus in the blood and may improve liver function.
Entecavir is an antiviral medication used to treat chronic hepatitis B infection by inhibiting viral replication.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- J05AF10
- RxNorm
- 306266
- Generic
- Entecavir
- Class
- atc-j05
- Brands
- Baraclude
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of chronic hepatitis B virus infection in adults and children (2 years and older) with evidence of active viral replication and liver inflammation.
Entecavir is a guanosine nucleoside analog that competitively inhibits HBV DNA polymerase, blocking the reverse transcription step needed for viral replication. This reduces HBV viral load in the body.
May cause serious lactic acidosis and hepatomegaly with steatosis, especially in females or obese patients. Not a cure for HBV; treatment is typically long-term. HIV testing is recommended before starting therapy. Dose adjustment needed for kidney impairment. Do not stop abruptly without medical supervision. Resistance may develop with long-term use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy