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Vedolizumab

Published: July 26, 2026Updated: July 26, 2026

Entyvio (vedolizumab) is a prescription biologic medication used to treat adults with ulcerative colitis and Crohn's disease, both types of inflammatory bowel disease. It is administered as an intravenous infusion and works by targeting specific immune cells to reduce inflammation in the digestive tract. This medication is typically used when other treatments have not been effective or tolerated.

Quick summary

Entyvio is a biologic infusion treatment for ulcerative colitis and Crohn's disease that reduces gut inflammation by blocking immune cell movement.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
1538138
Generic
Entyvio
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Entyvio is FDA-approved for treating adults with moderately to severely active ulcerative colitis and Crohn's disease, including patients who have had an inadequate response or intolerance to other therapies such as TNF blockers or immunomodulators.

Entyvio is a monoclonal antibody that specifically binds to the alpha-4-beta-7 integrin protein on the surface of certain white blood cells. By blocking this integrin, it prevents these cells from traveling to the gut lining and causing inflammation, thereby reducing disease activity in the gastrointestinal tract.

Entyvio is administered via intravenous infusion by a healthcare professional, typically at specialized infusion centers. Common side effects include headache, joint pain,发热, and infusion-related reactions. Patients should be monitored for infections during treatment as it may increase susceptibility to serious infections. A healthcare provider should evaluate current medications and vaccination history before starting therapy.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy