Epidiolex
Epidiolex is a prescription medication containing purified CBD (cannabidiol), a compound derived from the cannabis plant. It was approved by the FDA in 2018 and is used to treat certain rare forms of epilepsy in patients one year of age and older, including Dravet syndrome, Lennox-Gastaut syndrome, and tuberous sclerosis complex. It is available by prescription only and is the first FDA-approved plant-derived cannabis-based medicine.
Epidiolex is an FDA-approved CBD-based prescription medication used to treat rare forms of epilepsy.
Key facts at a glance
- RxNorm
- 2058901
- Generic
- Epidiolex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Epidiolex is indicated for the treatment of seizures associated with Dravet syndrome, Lennox-Gastaut syndrome, and tuberous sclerosis complex in patients one year of age and older. These are rare but severe forms of epilepsy that often do not respond well to traditional anti-epileptic medications.
The exact mechanism by which CBD produces its anticonvulsant effects is not fully understood. CBD is believed to work through multiple pathways, including modulation of the endocannabinoid system, reduction of neuronal excitability, and anti-inflammatory effects. As a purified pharmaceutical formulation, it contains minimal levels of THC (the psychoactive component of cannabis).
Epidiolex may cause side effects including drowsiness, decreased appetite, diarrhea, and liver abnormalities. It can interact with other medications, particularly those metabolized by the liver. Patients should not stop taking Epidiolex abruptly without medical supervision. This is a prescription-only medication and is not approved for recreational use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy