Eravacycline
Eravacycline is a broad-spectrum fluorocycline antibiotic used to treat complicated intra-abdominal infections in adults. It belongs to the tetracycline class of antibacterials and is effective against a range of Gram-positive and Gram-negative bacteria, including some drug-resistant strains. Administered intravenously, it provides an option when other antibiotics may not be suitable.
An intravenous fluorocycline antibiotic for treating complicated intra-abdominal infections in adults.
Key facts at a glance
- ATC
- J01AA13
- RxNorm
- 2055906
- Generic
- Eravacycline
- Class
- atc-j01
- Brands
- Xerava
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of complicated intra-abdominal infections (cIAI) in adult patients when other antibiotic options are not appropriate.
Eravacycline binds to the bacterial 30S ribosomal subunit, inhibiting protein synthesis and preventing bacterial growth. It is a synthetic tetracycline derivative with broad-spectrum activity against Gram-positive and Gram-negative bacteria.
Contraindicated in patients with known hypersensitivity to tetracyclines. Should not be used during pregnancy, breastfeeding, or in children under 8 years of age due to effects on bone and tooth development. Common adverse effects include gastrointestinal symptoms and infusion site reactions. Administered via intravenous infusion.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy