Ertugliflozin
Ertugliflozin is an SGLT2 inhibitor used to treat type 2 diabetes by helping the kidneys remove excess glucose from the bloodstream.
Ertugliflozin is a diabetes medication that helps lower blood sugar by causing the kidneys to excrete glucose through urine.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- A10BK04
- RxNorm
- 1992672
- Generic
- Ertugliflozin
- Class
- atc-a10
- Brands
- Segluromet, Steglatro, Steglujan
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ertugliflozin is indicated for the treatment of type 2 diabetes mellitus in adults to improve glycemic control. It may be used as monotherapy or in combination with other antihyperglycemic agents such as metformin, sitagliptin, or insulin when diet and exercise alone do not provide adequate blood sugar control.
Ertugliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by blocking the SGLT2 protein in the kidneys, which is responsible for reabsorbing glucose back into the bloodstream. By inhibiting this process, glucose is excreted in the urine, thereby lowering blood sugar levels.
Ertugliflozin is not indicated for use in patients with type 1 diabetes or diabetic ketoacidosis. Common side effects may include genital yeast infections, urinary tract infections, and increased urination. Patients should be aware of the risk of dehydration and should report any signs of ketoacidosis. Regular monitoring of kidney function is recommended during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy