Esbriet
Esbriet (pirfenidone) is an oral antifibrotic medication used to treat idiopathic pulmonary fibrosis (IPF), a chronic lung disease characterized by progressive scarring of lung tissue. It helps slow the decline in lung function and may reduce the risk of disease progression in appropriate patients.
Esbriet is a prescription medication used to treat idiopathic pulmonary fibrosis by reducing lung scarring.
Key facts at a glance
- RxNorm
- 1592280
- Generic
- Esbriet
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Esbriet is indicated for the treatment of idiopathic pulmonary fibrosis (IPF) in adults. IPF is a type of chronic lung disease where tissue deep in the lungs becomes scarred over time, leading to difficulty breathing and reduced oxygen transfer.
Esbriet is an antifibrotic agent. Although the exact mechanism is not fully understood, it is believed to reduce fibrosis (scarring) in the lungs by inhibiting the production of growth factors and other substances that promote tissue scarring and inflammation.
Common side effects may include nausea, rash, diarrhea, and photosensitivity (increased sensitivity to sunlight). Patients should avoid sun exposure and use sunscreen while taking this medication. Liver function monitoring is recommended during treatment. Always take Esbriet exactly as prescribed by your healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy