Esperoct
Esperoct is a brand-name recombinant antihemophilic factor (factor VIII) medication used to treat and prevent bleeding episodes in patients with hemophilia A. It is a long-acting form of factor VIII replacement therapy that is administered by intravenous injection. This medication can be used for on-demand treatment of acute bleeds as well as routine prophylaxis in both adults and children.
Esperoct is a long-acting recombinant factor VIII replacement therapy used to treat and prevent bleeding in patients with hemophilia A.
Key facts at a glance
- RxNorm
- 2275725
- Generic
- Esperoct
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Esperoct is indicated for the treatment and prevention of bleeding episodes in patients with hemophilia A (congenital factor VIII deficiency). It is used for on-demand treatment of acute bleeds, routine prophylaxis to prevent bleeding episodes, and perioperative management in adults and children.
Esperoct contains recombinant human coagulation factor VIII (turoctocog alfa pegol), which is a pegylated form of factor VIII designed for extended half-life. It temporarily replaces the missing factor VIII needed for blood clot formation, thereby enabling normal hemostasis in patients with hemophilia A.
Esperoct is administered by intravenous injection. Patients should be monitored for the development of factor VIII inhibitors (antibodies). Common side effects may include injection site reactions, hypersensitivity reactions, and in some cases, inhibitors may develop. This medication is typically prescribed and dosed under the supervision of a hematologist.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy