Estazolam
Estazolam is a benzodiazepine medication used primarily for the short-term treatment of insomnia. It works by enhancing the effects of GABA, a naturally occurring chemical in the brain that promotes calmness and sleep.
A benzodiazepine sleep medication used for short-term treatment of insomnia.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- N05CD04
- RxNorm
- 4077
- Generic
- Estazolam
- Class
- atc-n05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Estazolam is used for the short-term treatment of insomnia, helping with difficulty falling asleep, frequent nighttime awakenings, or early morning awakening.
Estazolam enhances the effect of GABA (gamma-aminobutyric acid) at GABA-A receptors in the brain, producing sedative and sleep-inducing effects.
Estazolam is typically prescribed for short-term use due to risks of dependence and tolerance. Common side effects include drowsiness, dizziness, and coordination problems. It should not be stopped abruptly after prolonged use due to potential withdrawal symptoms. Patients should avoid alcohol and activities requiring alertness while taking this medication.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy