Ethanolamine Oleate
Ethanolamine Oleate is a sclerosing agent used to treat varicose veins, esophageal varices, and hemorrhoids. It works by irritating the lining of blood vessels, causing inflammation and eventual fibrosis that closes off the affected vein.
Ethanolamine Oleate is an injectable sclerosing agent used to treat varicose veins and esophageal varices by causing treated veins to scar closed.
Key facts at a glance
- ATC
- C05BB01
- RxNorm
- 24460
- Generic
- Ethanolamine Oleate
- Class
- atc-c05
- Brands
- Ethamolin
- Availability
- rx
- Pregnancy
- C
- Lactation
- caution
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
second trimesteruse lowest effective dose
use only if clearly needed and benefits outweigh risks
fetal monitoring and uterine activity assessment
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse lowest effective dose
use only if benefits outweigh risks
fetal monitoring and preterm labor assessment
Use with caution and monitor for adverse effects.
lactation
breastfeedingnot recommended
discontinue breastfeeding or avoid drug; decision should be made considering importance of treatment to mother
monitor infant for adverse effects
geriatric
elderlydose reduction may be required based on organ function
use with caution due to potential decreased hepatic and renal function; start at lower end of dosing range
monitor renal function, hepatic function, and cardiovascular status
Use with caution and monitor for adverse effects.
pediatric_age
children adolescentsnot recommended
not recommended for use in pediatric populations due to limited safety and efficacy data
not applicable
Use of this medication in this population requires careful consideration of risks and benefits.
renal_impairment
moderate to severeuse with caution and monitor renal function
adjust dose based on renal function; consider reducing dose in patients with CrCl less than 50 mL/min
regular monitoring of renal function (creatinine, BUN)
Use with caution and monitor for adverse effects.
hepatic_impairment
cirrhosisdose adjustment may be required based on severity
use with caution in patients with hepatic impairment; this is the primary indication population for variceal treatment but requires careful monitoring
monitor liver function tests, coagulation parameters, and for signs of hepatic encephalopathy
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class information
Common uses
Common therapeutic uses
Mechanism of action
Pharmacological mechanism
Primarily used to treat esophageal varices (dilated veins in the esophagus that can bleed) and hemorrhoids. May also be used for varicose veins in the legs.
As a sclerosing agent, it causes chemical irritation to the inner lining of blood vessels, triggering inflammation that leads to fibrosis (scarring) and eventual closure of the treated vein.
Administered by injection directly into the affected vein by a healthcare professional. Requires careful technique due to risk of tissue damage if administered incorrectly. May cause pain at injection site. Contraindicated in patients with acute infections or certain vascular conditions. Monitor for allergic reactions.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy