Etofenamate
Etofenamate is a topical non-steroidal anti-inflammatory drug (NSAID) belonging to the anthranilic acid derivatives class. It is primarily used to treat musculoskeletal pain and inflammation, particularly for conditions affecting muscles, tendons, and joints.
Etofenamate is a topical NSAID used to relieve pain and inflammation associated with musculoskeletal conditions.
Key facts at a glance
- ATC
- M02AA06
- RxNorm
- 24608
- Generic
- Etofenamate
- Class
- atc-m02
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- gel
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Etofenamate is indicated for the topical treatment of painful musculoskeletal conditions including osteoarthritis, rheumatoid arthritis, soft tissue injuries such as sprains and strains, tendinitis, and localized forms of rheumatism affecting muscles and joints.
As an NSAID, etofenamate works by inhibiting cyclooxygenase (COX) enzymes, which reduces the synthesis of prostaglandins—chemicals involved in inflammation, pain, and fever. The topical formulation allows direct delivery to affected tissues while minimizing systemic absorption.
Etofenamate is for external use only and should not be applied to broken skin, eyes, or mucous membranes. Common side effects may include local skin reactions such as redness or irritation. Patients with known hypersensitivity to NSAIDs, aspirin, or other anthranilic acid derivatives should avoid this medication. Systemic side effects are generally lower compared to oral NSAIDs due to limited systemic absorption.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy