Etonogestrel
Etonogestrel is a synthetic progestogen hormone used primarily as a long-acting reversible contraceptive. It is the active ingredient in contraceptive implants and works by preventing ovulation and thickening cervical mucus to prevent sperm from reaching an egg. This medication is suitable for women seeking extended contraception coverage without daily intervention.
Etonogestrel is a progestogen hormone used in contraceptive implants to prevent pregnancy by stopping ovulation and blocking sperm.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- G03AC08
- RxNorm
- 14584
- Generic
- Etonogestrel
- Class
- atc-g03
- Brands
- Nexplanon, EluRyng, Haloette, Enilloring, NuvaRing
- Availability
- rx
- Lactation
- unknown
- Routes
- vaginal
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primary use is long-acting reversible contraception (LARC). The etonogestrel implant provides extended pregnancy prevention, typically lasting several years, and is reversible upon removal.
As a progestogen, etonogestrel suppresses the release of luteinizing hormone (LH), which inhibits ovulation. It also thickens cervical mucus to create a barrier against sperm and may alter the uterine lining to reduce implantation likelihood.
Must be inserted and removed by a qualified healthcare provider. Common side effects may include menstrual changes, headache, and mood changes. Not suitable for women with certain medical conditions; complete medical history should be discussed with a healthcare provider before use. Does not protect against sexually transmitted infections.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy