Etravirine
Etravirine is an antiretroviral medication classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infection. It is typically prescribed as part of combination therapy for patients who have developed resistance to other antiretroviral drugs. The medication works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of HIV.
Etravirine is an HIV-1 treatment drug that inhibits viral replication by targeting the reverse transcriptase enzyme.
Key facts at a glance
- ATC
- J05AG04
- RxNorm
- 475969
- Generic
- Etravirine
- Class
- atc-j05
- Brands
- Intelence
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of HIV-1 infection in combination with other antiretroviral agents, particularly in treatment-experienced patients with virus resistant to other NNRTIs and other antiretrovirals.
Etravirine is a non-nucleoside reverse transcriptase inhibitor that binds directly to reverse transcriptase, blocking the active site and preventing the conversion of viral RNA to DNA, thereby inhibiting viral replication.
Should always be used in combination with other antiretrovirals; effectiveness may be reduced by certain concomitant medications; skin reactions including serious cases have been reported; dosage is typically 200mg twice daily taken after a meal.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy