Exjade
Exjade (deferasirox) is an oral iron chelating agent used to treat chronic iron overload in patients who receive regular blood transfusions due to conditions such as thalassemia, sickle cell disease, or other anemias. It may also be used in patients with non-transfusion-dependent thalassemia syndromes who have iron overload. The medication works by binding to excess iron in the body and helping eliminate it through urine and feces.
Exjade is an iron chelator used to treat iron overload in patients requiring regular blood transfusions or with certain thalassemia syndromes.
Key facts at a glance
- RxNorm
- 614084
- Generic
- Exjade
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Exjade is indicated for the treatment of chronic iron overload due to blood transfusions in patients with beta-thalassemia, sickle cell disease, and other transfusion-dependent anemias aged 2 years and older. It is also used for chronic iron overload in patients with non-transfusion-dependent thalassemia syndromes aged 10 years and older.
Exjade is an iron chelator that selectively binds to iron molecules, forming a stable complex that can be eliminated from the body primarily through feces and to a lesser extent through urine. This helps reduce excess iron stored in organs such as the liver, heart, and endocrine glands.
Exjade requires regular monitoring of kidney and liver function, as well as serum ferritin levels to assess treatment response. Common side effects may include gastrointestinal symptoms, skin rash, and increases in serum creatinine. Tablets should be dispersed in water or juice and taken on an empty stomach. Patients should be advised to report any signs of kidney or liver problems, severe stomach pain, or allergic reactions to their healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy