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Factive

Published: July 26, 2026Updated: July 26, 2026

Factive (gemifloxacin) is a fluoroquinolone antibiotic used to treat certain bacterial infections, primarily respiratory tract infections such as community-acquired pneumonia and acute bacterial exacerbations of chronic bronchitis. It works by inhibiting bacterial enzymes necessary for DNA replication, effectively killing susceptible bacteria. This medication is available by prescription only and should be used as directed by a healthcare provider.

Quick summary

Factive is a prescription fluoroquinolone antibiotic used to treat respiratory bacterial infections.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
402085
Generic
Factive
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Factive is used to treat community-acquired pneumonia and acute bacterial exacerbations of chronic bronchitis caused by susceptible bacteria. It is important to note that this medication is not effective against viral infections like the common cold or flu.

Factive belongs to the fluoroquinolone class of antibiotics. It works by inhibiting two key bacterial enzymes—DNA gyrase and topoisomerase IV—which are essential for bacterial DNA replication, transcription, repair, and recombination. By disrupting these processes, the medication effectively kills susceptible bacteria.

Common side effects may include diarrhea, nausea, and headache. Fluoroquinolones have been associated with serious adverse effects including tendinitis, tendon rupture, peripheral neuropathy, and central nervous system effects. Patients should inform their doctor of any history of tendon disorders, seizures, or heart rhythm abnormalities. This medication may interact with certain antacids, blood thinners, and other medications. Always complete the full course of treatment as prescribed, even if symptoms improve.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy