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Fatal-Plus

Published: July 26, 2026Updated: July 26, 2026

Fatal-Plus is a brand-name veterinary euthanasia solution containing pentobarbital sodium. It is used by licensed veterinarians to provide humane and painless death for animals in medical settings. The drug works by rapidly inducing deep general anesthesia followed by death through respiratory depression and circulatory collapse.

Quick summary

Fatal-Plus is a veterinary euthanasia medication used to humanely end an animal's life in medical settings.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
1602557
Generic
Fatal-Plus
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Humane euthanasia of animals including dogs, cats, and other small animals in veterinary practice, animal shelters, and research facilities when medically appropriate.

Fatal-Plus contains pentobarbital, which acts as a central nervous system depressant. It rapidly induces deep anesthesia before causing respiratory depression and cardiac arrest.

This medication must only be administered by licensed veterinarians or trained personnel in accordance with applicable laws and regulations. Proper handling, disposal, and record-keeping are required. It should not be used in food-producing animals.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy