Fenbufen
Fenbufen is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid derivative class used to relieve pain, reduce inflammation, and decrease fever. It was primarily prescribed for the treatment of osteoarthritis, rheumatoid arthritis, and related musculoskeletal conditions.
Fenbufen is an NSAID used to treat arthritis and pain by reducing inflammation.
Key facts at a glance
- ATC
- M01AE05
- RxNorm
- 24830
- Generic
- Fenbufen
- Class
- atc-m01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Fenbufen was indicated for the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute musculoskeletal disorders such as sprains and strains. It was also used for pain management associated with these conditions.
Like other NSAIDs, fenbufen works by inhibiting the cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2, which are responsible for producing prostaglandins. Prostaglandins are inflammatory mediators that contribute to pain, swelling, and fever. By blocking their production, fenbufen reduces inflammation and associated symptoms.
Common side effects include gastrointestinal disturbances such as nausea and dyspepsia. As with other NSAIDs, it may increase cardiovascular risk and can cause kidney or liver impairment with prolonged use. Fenbufen has been withdrawn from some markets due to reports of severe liver toxicity. Patients should use the lowest effective dose for the shortest duration and avoid in patients with active peptic ulcer disease or severe renal impairment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy