Fenfluramine
Fenfluramine is a serotonin agonist medication used as an adjunctive treatment for seizures associated with Dravet syndrome and Lennox-Gastaut syndrome, two severe forms of epilepsy.
Fenfluramine is a serotonin agonist used to help control seizures in patients with Dravet syndrome and Lennox-Gastaut syndrome.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- A08AA02
- RxNorm
- 4328
- Generic
- Fenfluramine
- Class
- atc-a08
- Brands
- Fintepla
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Adjunctive treatment for seizures associated with Dravet syndrome and Lennox-Gastaut syndrome in patients 2 years of age and older
Acts as an agonist at serotonin 5-HT2 receptors, increasing serotonin activity in the brain; the precise antiepileptic mechanism is not fully understood
Requires echocardiogram monitoring before and during treatment due to risk of valvular heart disease and pulmonary arterial hypertension. Use with caution in patients with history of depression or suicidal ideation. Do not exceed prescribed dosing.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy