Fenoprofen
Fenoprofen is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which reduces the production of inflammatory prostaglandins in the body. This medication is typically prescribed for conditions involving pain and inflammation such as arthritis and other musculoskeletal disorders.
Fenoprofen is an NSAID that relieves pain, inflammation, and fever by inhibiting COX enzymes.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- M01AE04
- RxNorm
- 4331
- Generic
- Fenoprofen
- Class
- atc-m01
- Brands
- Fenopron, Nalfon
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory conditions. Also used for mild to moderate pain relief and fever reduction.
Fenoprofen inhibits cyclooxygenase enzymes (COX-1 and COX-2), blocking the production of prostaglandins that cause inflammation, pain, and fever.
Like other NSAIDs, fenoprofen carries risks of gastrointestinal bleeding, ulcers, and cardiovascular events. It may impair kidney function and increase bleeding risk, especially when combined with blood thinners. Use with caution in patients with a history of stomach ulcers, heart disease, or kidney problems.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy