Ferric Derisomaltose
Ferric derisomaltose is an intravenous iron replacement medication used to treat iron deficiency anemia when oral iron supplements are inadequate or poorly tolerated. It delivers iron directly to the bloodstream, where it binds to transferrin and is transported to bone marrow for incorporation into hemoglobin, effectively replenishing depleted iron stores.
An intravenous iron formulation that treats iron deficiency anemia by delivering iron directly for hemoglobin production.
Key facts at a glance
- RxNorm
- 2274394
- Generic
- Ferric Derisomaltose
- Class
- unclassified
- Brands
- Monoferric
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of iron deficiency anemia in adults, particularly when oral iron therapy is ineffective, not tolerated, or when rapid iron replenishment is required. Common scenarios include chronic kidney disease, inflammatory conditions affecting iron absorption, and significant blood loss.
Ferric derisomaltose consists of iron (III) hydroxide complexed with derisomaltose, an iron carbohydrate oligosaccharide. After intravenous administration, the complex releases iron, which binds to transferrin for transport through the bloodstream to bone marrow erythroid precursor cells, where it is incorporated into hemoglobin.
Administered as a single or divided intravenous infusion. Dosing is calculated based on patient weight and iron deficit. Monitor for hypersensitivity reactions including anaphylaxis, particularly during or shortly after infusion. May cause transient skin discoloration at injection site. Not for use in conditions where iron utilization is impaired.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy