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Ferrous Gluconate

Published: July 26, 2026Updated: August 24, 2026

Ferrous gluconate is an oral iron supplement used to treat and prevent iron deficiency anemia. It provides elemental iron that helps restore normal red blood cell production and hemoglobin levels in patients with low iron stores.

Quick summary

Ferrous gluconate is an iron supplement that treats iron deficiency anemia by replenishing iron stores needed for hemoglobin production.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 24, 2026Editorial policy

Key facts at a glance

ATC
B03AA03
RxNorm
24942
Generic
Ferrous Gluconate
Class
atc-b03
Brands
Fergon, Ferate
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
500mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
250mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
400mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose of approximately 10,000 mg of ferrous gluconate (containing about 1,200 mg elemental iron) may cause serious toxicity in adults
Chronic overdose: Repeated daily doses exceeding 200-500 mg of elemental iron can lead to chronic iron overload and organ damage
Immediate actions
Gastric lavage within 1-2 hours of ingestion, activated charcoal (though less effective for iron), whole bowel irrigation for large ingestions, supportive care including IV fluids and monitoring
Antidote
Deferoxamine(Highly effective when administered early, binding free iron and promoting its excretion)
Poison Control: 1-800-222-1222

Special Populations

10 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

avoid high doses, use only if iron deficiency confirmed

Monitor

regular prenatal monitoring, check hemoglobin levels

Use with caution and monitor for adverse effects.

✓

pregnancy

second third trimester
safe
FDA Category
C
Dose Adjustment

standard adult dosing

Key Recommendations

commonly prescribed for pregnancy-related iron deficiency

Monitor

routine prenatal checkups, hemoglobin monitoring

✓

lactation

safe
FDA Category
C
Dose Adjustment

standard adult dosing

Key Recommendations

compatible with breastfeeding, continue supplementation if needed

Monitor

monitor maternal hemoglobin

✓

pediatric_age

children 2 12 years
safe
FDA Category
C
Dose Adjustment

weight-based dosing typically 3-6 mg/kg/day of elemental iron

Key Recommendations

use liquid formulation for accurate dosing, divide doses

Monitor

monitor for GI side effects, periodic hemoglobin checks

⚠

pediatric_age

infants under 2 years
caution
FDA Category
C
Dose Adjustment

requires physician supervision, typically 1-2 mg/kg/day

Key Recommendations

use under medical supervision only, special formulations available

Monitor

close medical monitoring required

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly 65 years and older
caution
FDA Category
C
Dose Adjustment

start with lower dose, may need dose reduction

Key Recommendations

monitor GI tolerance, consider lower frequency dosing

Monitor

regular hemoglobin and ferritin monitoring

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild to moderate renal impairment
caution
FDA Category
C
Dose Adjustment

may require dose adjustment based on renal function

Key Recommendations

use with caution, monitor renal function

Monitor

monitor renal function and iron parameters

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe renal impairment dialysis
caution
FDA Category
C
Dose Adjustment

typically requires dose adjustment and intravenous iron may be preferred

Key Recommendations

coordination with nephrologist recommended

Monitor

frequent monitoring of iron studies and renal function

Use with caution and monitor for adverse effects.

✓

hepatic_impairment

mild to moderate hepatic impairment
safe
FDA Category
C
Dose Adjustment

no specific adjustment needed

Key Recommendations

generally well tolerated

Monitor

standard iron parameter monitoring

⚠

alcohol_users

chronic alcohol use
caution
FDA Category
C
Dose Adjustment

may require higher doses due to malabsorption

Key Recommendations

assess for concomitant liver disease, monitor closely

Monitor

monitor liver function and iron studies

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

Commonly prescribed since

Value:1990s

General prescribing information for iron supplements

drug_classWHO
2023

Drug class

Value:Iron supplement

ATC code B03A (Antianemic preparations)

usageMedical guidelines
2023

Common uses

Value:Treatment of iron deficiency anemia

Common therapeutic uses for ferrous gluconate

pharmacokineticsFDA
2023

Bioavailability

Value:10-15%

Iron absorption from ferrous gluconate in the gastrointestinal tract

Treatment and prevention of iron deficiency anemia due to conditions such as pregnancy, poor dietary iron intake, blood loss, or malabsorption syndromes.

Provides elemental iron that is absorbed in the gastrointestinal tract and incorporated into hemoglobin, enabling red blood cells to carry oxygen throughout the body.

Take on an empty stomach with vitamin C for optimal absorption. Common side effects include gastrointestinal upset, constipation, and dark stools. Separate administration from antibiotics and thyroid medications by at least 2 hours. Keep out of reach of children as iron overdose can be dangerous.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy