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Ferrous Sulfate

Published: July 26, 2026Updated: August 26, 2026

Ferrous sulfate is an iron supplement used to treat or prevent iron deficiency anemia, a condition where the body lacks enough healthy red blood cells due to low iron levels. It is commonly prescribed for individuals with anemia caused by pregnancy, poor diet, blood loss, or certain medical conditions that impair iron absorption.

Quick summary

Ferrous sulfate is an oral iron supplement that treats iron deficiency anemia by replenishing iron stores in the body.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 26, 2026Editorial policy

Key facts at a glance

ATC
B03AA07
RxNorm
24967
Generic
Ferrous Sulfate
Class
atc-b03
Brands
Slow-Fe, Feosol, Fer-in-Sol, Folitab
Availability
otc
Pregnancy
A
Lactation
safe
Half-life (h)
0
Onset (min)
0
Duration (h)
0
Routes
oral, topical
Forms
tablet, extended-release tablet, capsule, oral solution, drops, elixir, syrup
Regions
United States, Canada, United Kingdom, European Union, Australia, India, China, Brazil, Japan
Monitoring
hemoglobin, hematocrit, serum ferritin, transferrin saturation, reticulocyte count

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
500mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
250mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
400mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose of approximately 10,000 mg (10 grams) of ferrous sulfate may cause serious toxicity in adults
Chronic overdose: Repeated doses exceeding 2-3 times the recommended daily dose over weeks to months can lead to iron accumulation and organ damage
Immediate actions
Gastric lavage within 1-2 hours of ingestion, whole bowel irrigation for sustained-release preparations, supportive care for hypotension and metabolic acidosis
Antidote
Deferoxamine(Highly effective when administered early, binds to free iron for excretion)
Poison Control: 1-800-222-1222

Special Populations

8 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

use only if iron deficiency confirmed

Key Recommendations

avoid unnecessary supplementation, only use when benefits outweigh risks

Monitor

regular prenatal checkups and hemoglobin monitoring

Use with caution and monitor for adverse effects.

✓

pregnancy

second trimester
safe
FDA Category
C
Dose Adjustment

standard adult dosing

Key Recommendations

commonly prescribed for iron deficiency anemia in pregnancy

Monitor

routine hemoglobin and hematocrit checks

✓

pregnancy

third trimester
safe
FDA Category
C
Dose Adjustment

standard adult dosing

Key Recommendations

important for maternal iron stores and fetal iron储备

Monitor

monitor iron studies and hemoglobin

✓

lactation

breastfeeding
safe
FDA Category
C
Dose Adjustment

standard adult dosing

Key Recommendations

compatible with breastfeeding, iron is secreted in minimal amounts in breast milk

Monitor

maternal hemoglobin monitoring

⚠

pediatric_age

children 2 12 years
caution
FDA Category
C
Dose Adjustment

weight-based dosing required

Key Recommendations

use pediatric formulations, keep out of reach of children to prevent overdose

Monitor

close supervision of dosing, monitor for toxicity

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly 65 years
caution
FDA Category
C
Dose Adjustment

start with lower dose

Key Recommendations

may need lower doses due to decreased GI tolerance, consider alternative formulations

Monitor

monitor for GI side effects and hemoglobin response

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild to moderate
caution
FDA Category
C
Dose Adjustment

may require dose adjustment

Key Recommendations

patients on dialysis may require higher doses due to blood loss

Monitor

regular monitoring of iron studies and renal function

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild to moderate
caution
FDA Category
C
Dose Adjustment

use with caution

Key Recommendations

monitor liver function and iron studies

Monitor

regular monitoring of ferritin and liver enzymes

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

Commonly prescribed since

Value:1950s

General prescribing information for iron deficiency treatment

drug_classWHO
2023

Drug class

Value:Iron supplement

Mineral supplement class information

usageMedical guidelines
2023

Common uses

Value:Iron deficiency anemia treatment

Primary therapeutic indication

pharmacokineticsFDA
2023

Typical elemental iron content

Value:20%

Standard ferrous sulfate composition

Ferrous sulfate is used to treat and prevent iron deficiency anemia, including anemia associated with pregnancy, menstrual blood loss, gastrointestinal bleeding, surgery, dialysis, and inadequate dietary iron intake.

Ferrous sulfate provides elemental iron, which is a key component of hemoglobin—the protein in red blood cells that carries oxygen throughout the body. By replenishing iron stores, it helps restore normal hemoglobin levels and improves oxygen transport in the blood.

Take on an empty stomach with water or juice for best absorption (unless stomach upset occurs, then take with food). Avoid taking with antacids, calcium supplements, or dairy products as they can reduce absorption. Common side effects include constipation, dark stools, nausea, and stomach upset. Store away from children as iron overdose can be dangerous.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy