Filspari
Filspari is a brand-name prescription medication approved for the treatment of IgA nephropathy (also known as Berger's disease), a kidney disorder characterized by inflammation and damage to the kidney's filtering structures. It works by targeting two specific receptors to help reduce proteinuria (excess protein in the urine) and slow disease progression in patients at risk of developing chronic kidney disease.
Filspari is a dual-action medication used to treat IgA nephropathy by reducing proteinuria and slowing kidney disease progression.
Key facts at a glance
- RxNorm
- 2630541
- Generic
- Filspari
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Filspari is indicated for the treatment of IgA nephropathy (IgAN) in adults who are at risk of progressive disease, helping to reduce proteinuria.
Filspari is a dual endothelin A receptor and angiotensin II type 1 receptor antagonist. By blocking these receptors, it helps reduce inflammation and kidney damage that leads to proteinuria in IgA nephropathy.
Filspari is contraindicated in pregnancy due to potential fetal harm. Common side effects may include edema, hypotension, hyperkalemia, and dizziness. Patients require regular monitoring of kidney function, blood pressure, and proteinuria levels during treatment. Liver function should also be monitored as hepatotoxicity has been reported.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy