Finerenone
Finerenone is a nonsteroidal, selective mineralocorticoid receptor antagonist used to treat chronic kidney disease (CKD) in adults with type 2 diabetes. It works by blocking aldosterone-mediated mineralocorticoid receptor activation, reducing kidney damage and cardiovascular risk associated with overactivation of this pathway in the kidneys and heart.
Finerenone is a kidney-protecting medication for adults with chronic kidney disease and type 2 diabetes that works by blocking harmful aldosterone activity.
Key facts at a glance
- ATC
- C03DA05
- RxNorm
- 2562811
- Generic
- Finerenone
- Class
- atc-c03
- Brands
- Kerendia
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of chronic kidney disease (CKD) in adults with type 2 diabetes to reduce the risk of kidney disease progression and cardiovascular events such as heart attack, stroke, and heart failure.
Finerenone selectively blocks the mineralocorticoid receptor (MR) activated by aldosterone. By preventing MR overactivation, it reduces sodium reabsorption and the inflammatory and fibrotic processes in kidney tissue that lead to progressive kidney damage and cardiovascular complications.
Requires regular monitoring of serum potassium and kidney function (eGFR). Contraindicated in patients with severe kidney impairment (eGFR <25), adrenal insufficiency, and concurrent use of strong CYP3A4 inhibitors. Common side effects include hyperkalemia, hypotension, and hyponatremia. Not recommended during pregnancy.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy