Firazyr
Firazyr (icatibant) is a prescription medication used to treat acute attacks of hereditary angioedema (HAE) in adults aged 18 years and older. It works by blocking the action of bradykinin, a substance in the body that causes swelling and inflammation during HAE attacks. The medication is administered as a subcutaneous injection, typically in the abdomen or thigh area.
Firazyr is a brand-name injectable medication used to treat acute hereditary angioedema attacks in adults by blocking bradykinin action.
Key facts at a glance
- RxNorm
- 1148142
- Generic
- Firazyr
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Firazyr is indicated for the treatment of acute attacks of hereditary angioedema (HAE) in adults aged 18 and older with diagnosed HAE due to C1-esterase inhibitor deficiency.
Firazyr contains the active ingredient icatibant, which is a bradykinin B2 receptor antagonist. It blocks the action of bradykinin, a natural substance in the body that causes increased vascular permeability and leads to the swelling, pain, and other symptoms associated with HAE attacks.
Firazyr is administered by subcutaneous injection, usually by a healthcare professional or self-injected after proper training. Common side effects may include injection site reactions (pain, redness, swelling), fever, or dizziness. Patients should seek emergency medical care if they experience symptoms of laryngeal angioedema. Pregnant or breastfeeding women should consult their healthcare provider before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy