Flupenthixol
Flupenthixol is an antipsychotic medication belonging to the thioxanthene class, primarily used to manage symptoms of schizophrenia and other psychotic disorders. In lower doses, it has also demonstrated efficacy in treating depressive symptoms. The medication works by modulating dopamine activity in the brain, helping to restore chemical balance and reduce psychotic symptoms such as hallucinations, delusions, and disorganized thinking.
Flupenthixol is an antipsychotic used to treat schizophrenia and related psychotic disorders, with additional applications in managing certain depressive conditions.
Key facts at a glance
- ATC
- N05AF01
- RxNorm
- 4495
- Generic
- Flupenthixol
- Class
- atc-n05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Flupenthixol is primarily prescribed for schizophrenia and other psychotic disorders characterized by symptoms such as hallucinations, delusions, and thought disturbances. It is also utilized in the treatment of moderate to severe depression, particularly when anxiety or apathy are prominent features. In some regions, it may be prescribed for severe anxiety or other mood-related conditions.
Flupenthixol exerts its therapeutic effects primarily by blocking dopamine D1 and D2 receptors in the brain's dopamine pathways. It also has affinity for serotonin receptors, which contributes to its broader pharmacological profile. This blockade of dopamine transmission helps reduce the positive symptoms of psychosis and, at lower doses, may enhance mood regulation.
Flupenthixol may cause side effects including drowsiness, extrapyramidal symptoms (such as tremor or muscle stiffness), weight gain, and orthostatic hypotension. It should not be used in patients with acute agitation,兴奋, or those who are unconscious. Patients should avoid alcohol during treatment and should not stop taking this medication abruptly without medical supervision. Regular monitoring by a healthcare provider is essential throughout treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy