Flutamide
Flutamide is a nonsteroidal antiandrogen medication primarily used in the treatment of advanced prostate cancer. It works by blocking the action of male hormones (androgens) on cancer cells, preventing them from growing and spreading. Often used in combination with other hormone therapies, it is particularly useful in managing prostate cancer that has spread to other parts of the body.
Flutamide is an antiandrogen drug used to treat prostate cancer by blocking the effects of male hormones on cancer cells.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- L02BB01
- RxNorm
- 4508
- Generic
- Flutamide
- Class
- atc-l02
- Brands
- Eulexin
- Availability
- rx
- Pregnancy
- D
- Lactation
- unsafe
- Routes
- oral
- Forms
- capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of metastatic or advanced prostate cancer, often used alongside gonadotropin-releasing hormone (GnRH) agonists to prevent initial testosterone surge, and sometimes prescribed for conditions like hirsutism in women or precocious puberty.
Flutamide competitively inhibits androgen receptors, blocking testosterone and dihydrotestosterone (DHT) from binding and exerting their androgenic effects on prostate tissue and prostate cancer cells.
May cause liver dysfunction requiring monitoring of liver enzymes; common side effects include hot flashes, breast tenderness, and gastrointestinal symptoms. Important to inform about potential interactions with other medications and the need for regular medical follow-up. Should not be used in women who are pregnant.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy