Follitropin Beta (Puregon): Patient Guide
Follitropin beta is a recombinant follicle-stimulating hormone (FSH) used to stimulate ovarian growth and egg development. It is prescribed for ovulation induction and ovarian stimulation before in vitro fertilization (IVF).
Follitropin beta is a daily injectable fertility medicine that must be individualized and closely monitored by a fertility specialist. Contact your healthcare team promptly for severe abdominal pain, swelling, breathing difficulty, or signs of a serious allergic reaction.
Key facts at a glance
- ATC
- G03GA06
- RxNorm
- 25357
- Generic
- Follitropin Beta
- Class
- atc-g03
- Brands
- Follistim
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 75-300 IU daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- not indicated
- Maximum
- consult physician
- Frequency
- not applicable
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- not indicated
- Maximum
- consult physician
- Frequency
- not applicable
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
11 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks; follitropin beta is indicated for ovulation induction and not for use in established pregnancy
regular fetal monitoring if used
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
second trimesteravoid
discontinue if pregnancy occurs during treatment
standard prenatal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
third trimesteravoid
not indicated for use during third trimester
standard prenatal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
lactation
breastfeedingavoid or discontinue breastfeeding
it is unknown whether follitropin beta is excreted in human breast milk; use with caution in nursing mothers
monitor infant for adverse effects
pediatric_age
prepubertalindividualize based on response
used for induction of spermatogenesis in males with hypogonadotropic hypogonadism; requires specialist pediatric endocrinology supervision
close monitoring of growth, bone age, and hormonal parameters
Use with caution and monitor for adverse effects.
pediatric_age
adolescentindividualize dosing
used in adolescents for hypogonadotropic hypogonadism; specialist supervision required
monitor hormonal levels, growth velocity, and bone maturation
Use with caution and monitor for adverse effects.
geriatric
elderlystart at lowest effective dose
limited clinical experience in patients over 65 years; use only when benefits clearly outweigh risks
monitor for cardiovascular and thromboembolic events
Use with caution and monitor for adverse effects.
renal_impairment
mildno specific dose adjustment recommended
use with caution; monitor renal function
monitor renal function periodically
Use with caution and monitor for adverse effects.
renal_impairment
moderate to severeconsider dose reduction
use with caution; limited data available on pharmacokinetics in severe renal impairment
close monitoring of renal function and clinical response
Use with caution and monitor for adverse effects.
hepatic_impairment
mildno specific dose adjustment recommended
use with caution; monitor liver function
monitor liver function tests
Use with caution and monitor for adverse effects.
hepatic_impairment
moderate to severeuse with caution
limited data available; use only if benefits clearly outweigh risks
close monitoring of liver function and clinical response
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class
Drug class information
Common uses
Common therapeutic uses
Mechanism of action
Pharmacological mechanism
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy