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Fosamax

Published: July 26, 2026Updated: July 26, 2026

Fosamax (alendronate) is a bisphosphonate medication used to treat and prevent osteoporosis in postmenopausal women and to increase bone mass in men with osteoporosis. It is also prescribed for Paget's disease of bone and steroid-induced osteoporosis. The medication works by slowing bone loss, which helps maintain strong bones and reduces the risk of fractures.

Quick summary

Fosamax is a bone-building medication used to treat and prevent osteoporosis by slowing bone loss and reducing fracture risk.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
114265
Generic
Fosamax
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment and prevention of postmenopausal osteoporosis, treatment of osteoporosis in men, treatment of glucocorticoid-induced osteoporosis, and Paget's disease of bone.

Fosamax inhibits osteoclast-mediated bone resorption, allowing osteoblasts to continue building bone. This helps increase bone mineral density and reduce the risk of fractures.

Must be taken first thing in the morning with a full glass of plain water, at least 30 minutes before any food, beverages, or other medications. Patients should remain upright (sitting or standing) for at least 30 minutes after taking to reduce risk of esophageal irritation. Not recommended for patients with severe kidney disease, low blood calcium, or difficulty swallowing. May cause rare but serious side effects including osteonecrosis of the jaw and atypical femur fractures with long-term use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy