Fosinopril
Fosinopril is an ACE inhibitor used to treat hypertension, heart failure, and to improve survival after heart attacks. It works by blocking the conversion of angiotensin I to angiotensin II, a substance that causes blood vessels to constrict. This leads to relaxed blood vessels and lower blood pressure.
Fosinopril is an ACE inhibitor that lowers blood pressure by preventing the formation of angiotensin II, a potent vasoconstrictor.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- C09AA09
- RxNorm
- 50166
- Generic
- Fosinopril
- Class
- atc-c09
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Fosinopril is indicated for the treatment of hypertension (high blood pressure) and heart failure. It may also be used to improve survival in patients who have had a heart attack and to slow the progression of kidney disease in diabetic patients.
Fosinopril is a prodrug that is converted in the body to fosinoprilat, which competitively inhibits angiotensin-converting enzyme (ACE). By blocking ACE, the drug prevents the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and lowering blood pressure.
Common side effects include dizziness, headache, and dry cough. Fosinopril should not be used during pregnancy as it may harm the unborn baby. Patients with a history of angioedema or those taking aliskiren should avoid this medication. Blood pressure and kidney function should be monitored during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy