Gabitril
Gabitril (tiagabine) is an antiepileptic medication used as adjunctive therapy to treat partial seizures in adults and children age 12 and older. It works by increasing levels of GABA, an inhibitory neurotransmitter in the brain, which helps reduce seizure activity.
Gabitril is an add-on seizure medication that increases GABA to help control partial seizures.
Key facts at a glance
- RxNorm
- 217243
- Generic
- Gabitril
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Gabitril is FDA-approved as adjunctive (add-on) treatment for partial seizures in patients 12 years and older. It is used when other antiepileptic medications alone are insufficient to control seizure activity.
Gabitril is a selective GABA reuptake inhibitor. It blocks the reuptake of GABA at presynaptic neurons, increasing GABA concentrations in the synaptic cleft and enhancing inhibitory neurotransmission in the brain.
Gabitril is not indicated for primary generalized seizures and may worsen certain seizure types. Abrupt discontinuation should be avoided due to seizure risk. Patients without epilepsy should not use this medication, as it has caused non-convulsive status epilepticus and new-onset seizures in individuals without seizure disorders. Common side effects include dizziness, somnolence, and nervousness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy