Gamma-Linolenate
Gamma-Linolenate (gamma-linolenic acid) is an omega-6 fatty acid supplement commonly derived from evening primrose oil, borage oil, and black currant seed oil. It is used primarily to support skin health, manage inflammatory conditions, and address hormone-related symptoms.
An omega-6 fatty acid supplement used to support skin health, manage inflammatory conditions, and address hormone-related symptoms.
Key facts at a glance
- RxNorm
- 618453
- Generic
- Gamma-Linolenate
- Class
- unclassified
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Gamma-Linolenate is used for atopic dermatitis (eczema), rheumatoid arthritis symptoms, premenstrual syndrome (PMS), cyclic mastalgia (breast pain), and diabetic neuropathy. It may also support general skin health and inflammatory responses.
Gamma-Linolenate converts to dihomo-gamma-linolenic acid (DGLA), a precursor to prostaglandin E1 (PGE1), an anti-inflammatory eicosanoid. This pathway helps modulate inflammatory responses and supports skin barrier function.
Generally well-tolerated, though mild gastrointestinal upset may occur. Those with seizure disorders should use caution. Consult a healthcare provider before use, particularly if pregnant, nursing, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy