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Gemifloxacin

Published: July 26, 2026Updated: August 20, 2026

Gemifloxacin is a fluoroquinolone antibiotic used to treat bacterial infections, particularly respiratory tract infections such as community-acquired pneumonia and acute bacterial exacerbations of chronic bronchitis. It works by inhibiting bacterial DNA replication enzymes, effectively killing susceptible bacteria. This medication is typically prescribed when other antibiotics are unsuitable.

Quick summary

Gemifloxacin is a fluoroquinolone antibiotic used to treat respiratory and other bacterial infections.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ATC
J01MA15
RxNorm
138099
Generic
Gemifloxacin
Class
atc-j01
Brands
Factive
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Gemifloxacin is indicated for the treatment of community-acquired pneumonia and acute bacterial exacerbations of chronic bronchitis. It may also be used for other respiratory tract infections caused by susceptible bacteria.

Gemifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which are essential enzymes for bacterial DNA replication, transcription, and repair. By blocking these enzymes, the medication prevents bacterial growth and leads to bacterial cell death.

Common side effects include nausea, diarrhea, and headache. Like other fluoroquinolones, it may cause tendinitis or tendon rupture, particularly in older adults. Patients should avoid excessive sun exposure and stay well hydrated during treatment. Not recommended for use in children, adolescents, or pregnant women due to potential effects on cartilage development.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy