Imatinib
Gleevec (imatinib) is a targeted cancer therapy known as a tyrosine kinase inhibitor. It works by blocking specific proteins that drive the growth of cancer cells, making it effective for certain blood cancers and tumors with specific genetic markers. This medication has revolutionized treatment for chronic myeloid leukemia and gastrointestinal stromal tumors.
Gleevec is a targeted therapy that blocks cancer cell growth by inhibiting specific tyrosine kinases, primarily used for certain leukemias and tumors.
Key facts at a glance
- RxNorm
- 282386
- Generic
- Gleevec
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Gleevec is primarily used to treat chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and certain other cancers with specific genetic mutations such as the Philadelphia chromosome or c-KIT mutations.
Gleevec inhibits tyrosine kinases—specifically BCR-ABL, c-KIT, and PDGFR—which are proteins that drive abnormal cell growth and division in certain cancers. By blocking these proteins, it helps slow or stop cancer progression.
Gleevec should be taken with food and a large glass of water to reduce stomach upset. Common side effects may include fluid retention, fatigue, and nausea. Regular blood tests are needed to monitor blood counts and liver function. Patients should avoid grapefruit juice as it may interact with the medication.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy