Lomustine
Gleostine (lomustine) is an oral alkylating agent used in the treatment of certain cancers, including brain tumors and Hodgkin's lymphoma. It works by interfering with DNA replication in cancer cells, preventing their growth and multiplication.
Gleostine is a prescription chemotherapy medication used to treat certain brain tumors and lymphomas.
Key facts at a glance
- RxNorm
- 1545771
- Generic
- Gleostine
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Gleostine is used to treat certain types of brain tumors (such as glioblastoma and astrocytoma) and Hodgkin's lymphoma. It may be used alone or in combination with other cancer treatments.
As an alkylating agent, Gleostine works by binding to DNA in cancer cells, causing damage that prevents the cells from replicating. This slows or stops the growth of cancer cells.
Gleostine is taken by mouth as a single dose, typically once every 6 weeks. Major side effects include delayed bone marrow suppression (blood count drops may occur 4-6 weeks after dosing), liver toxicity, and lung problems. Regular blood tests are required to monitor blood counts and liver function. Common side effects include nausea, vomiting, and hair loss.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy