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Gluconolactone

Published: July 26, 2026Updated: August 31, 2026

Gluconolactone is a polyhydroxy acid (PHA) commonly used in dermatological and cosmetic preparations for skin care. It provides antioxidant protection, gentle exfoliation, and hydration support. This compound is frequently incorporated into anti-aging formulations and products designed for sensitive skin due to its温和 properties compared to traditional alpha-hydroxy acids.

Quick summary

A polyhydroxy acid used in skincare products for gentle exfoliation and antioxidant protection.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 31, 2026Editorial policy

Key facts at a glance

RxNorm
25842
Generic
Gluconolactone
Class
unclassified
Brands
Renacidin
Availability
rx
Pregnancy
C
Lactation
caution
Routes
—
Forms
solution
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used topically for anti-aging skin care, hyperpigmentation, uneven skin texture, and general skin conditioning. May also be found in products for sensitive skin due to its gentle formulation profile.

Functions as a gentle exfoliant by helping to break down dead skin cells on the skin's surface. Also provides antioxidant benefits and helps attract moisture to the skin, supporting overall skin barrier function.

Primarily used in cosmetic and dermatological preparations rather than systemic medications. Generally considered well-tolerated with less irritation potential than AHAs. Sun protection is recommended when using exfoliating compounds. Not typically used as an oral or injectable medication.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy