Metformin
Glucophage (metformin) is an oral antidiabetic medication used to manage type 2 diabetes by lowering blood glucose levels. It is typically prescribed alongside diet and exercise to improve glycemic control in adults and sometimes children over 10 years old with type 2 diabetes.
Glucophage is a first-line diabetes medication that helps control blood sugar in people with type 2 diabetes.
Key facts at a glance
- RxNorm
- 151827
- Generic
- Glucophage
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Glucophage is primarily used to treat type 2 diabetes mellitus in adults and children 10 years and older. It may also be used in combination with other diabetes medications or insulin when needed. Sometimes prescribed off-label for conditions like polycystic ovary syndrome (PCOS) and insulin resistance.
Glucophage belongs to the biguanide class of medications. It works by decreasing the amount of glucose produced by the liver, reducing the absorption of glucose from the intestines, and improving the body's response to insulin. Unlike some diabetes medications, it does not cause hypoglycemia when used alone.
Glucophage should be taken with meals to reduce stomach side effects like nausea and diarrhea. It is contraindicated in patients with severe kidney disease, liver disease, or conditions that can cause tissue hypoxia. Rare but serious side effects include lactic acidosis. Regular kidney function monitoring is recommended during treatment. Alcohol should be avoided or limited as it can increase the risk of lactic acidosis.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy