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Glucose (Dextrose): Uses, Side Effects, and Safety

Published: July 22, 2026Updated: July 22, 2026

Glucose, also called dextrose, is a carbohydrate used to raise blood sugar when it becomes dangerously low. It may be given by mouth as a glucose product or by injection in a healthcare setting, depending on the formulation and the urgency of treatment.

Quick summary

Glucose can treat low blood sugar, but the correct amount and route depend on the product and the situation. Follow the package instructions or a clinician’s directions, and never give oral glucose to someone who is unconscious or unable to swallow safely.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 22, 2026Editorial policy

Key facts at a glance

ATC
V04CA02
Generic
Glucose
Class
glucose
Brands
Glutose, Insta-Glucose
Availability
behind_counter
Pregnancy
C
Lactation
safe
Onset (min)
5
Duration (h)
1
Routes
oral, iv
Forms
gel, injection, tablet
Regions
CN, US, EU, JP
Monitoring
blood-glucose

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
15-20g
Maximum
consult physician
Frequency
as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
0.5-1 g/kg
Maximum
consult physician
Frequency
as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
15g
Maximum
consult physician
Frequency
as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Glucose (simple sugar) does not have a traditional toxic single dose; excess glucose is metabolized by the body. Concern primarily exists for patients with diabetes experiencing severe hyperglycemia.
Chronic overdose: Not applicable - glucose is a naturally occurring carbohydrate that the body continuously processes
Immediate actions
Monitor blood glucose, administer insulin as prescribed, fluid replacement, correct electrolyte imbalances
Antidote
Insulin (for hyperglycemia management)(Essential for lowering dangerously high blood glucose levels)
Poison Control: 1-800-222-1222

Special Populations

11 groups
✓

pregnancy

first trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

use as needed for hypoglycemia, maintain normal blood glucose levels

Monitor

regular blood glucose monitoring

✓

pregnancy

second trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

continue glucose supplementation as needed for hypoglycemia management

Monitor

regular blood glucose monitoring

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

monitor closely

Key Recommendations

avoid excessive glucose administration, monitor for gestational diabetes

Monitor

regular blood glucose monitoring, gestational diabetes screening

Use with caution and monitor for adverse effects.

✓

lactation

breastfeeding
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

glucose is naturally present in breast milk, use as needed

Monitor

no specific monitoring required

⚠

pediatric_age

neonates
caution
FDA Category
C
Dose Adjustment

weight-based dosing

Key Recommendations

use under medical supervision, monitor blood glucose closely

Monitor

frequent blood glucose monitoring

Use with caution and monitor for adverse effects.

✓

pediatric_age

children
safe
FDA Category
C
Dose Adjustment

weight-based dosing

Key Recommendations

appropriate for treating hypoglycemia in children

Monitor

regular blood glucose monitoring

⚠

geriatric

elderly
caution
FDA Category
C
Dose Adjustment

monitor closely

Key Recommendations

use with caution in elderly with diabetes or metabolic disorders

Monitor

regular blood glucose monitoring

Use with caution and monitor for adverse effects.

✓

renal_impairment

mild to moderate
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

use as needed, glucose is metabolized

Monitor

monitor blood glucose

⚠

renal_impairment

severe
caution
FDA Category
C
Dose Adjustment

use with caution

Key Recommendations

monitor for fluid overload with IV glucose

Monitor

frequent blood glucose and fluid status monitoring

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild to moderate
caution
FDA Category
C
Dose Adjustment

monitor closely

Key Recommendations

liver metabolizes glucose, monitor blood levels

Monitor

regular blood glucose monitoring

Use with caution and monitor for adverse effects.

⚠

alcohol_users

chronic alcohol use
caution
FDA Category
C
Dose Adjustment

monitor closely

Key Recommendations

alcohol can cause hypoglycemia, glucose may be needed but monitor closely

Monitor

frequent blood glucose monitoring

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

Commonly prescribed since

Value:1970s

Emergency glucose products for hypoglycemia treatment

drug_classWHO
2023

Drug class

Value:Monosaccharide/Carbohydrate

Chemical classification of glucose

usageMedical guidelines
2023

Common uses

Value:Treatment of hypoglycemia

Primary therapeutic indication for glucose products

administrationFDA
2023

Route of administration

Value:Oral, Intravenous

Methods of administering glucose products

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy