Vadadustat
Gohibic (vilobelimab) is a monoclonal antibody medication that targets the complement system by binding to C5a, a protein involved in inflammatory responses. It was granted Emergency Use Authorization for treating severe COVID-19 in hospitalized adults. The medication works by inhibiting C5a-mediated inflammation, which is thought to play a role in the severe inflammatory response seen in critical COVID-19 cases.
Gohibic is an anti-inflammatory monoclonal antibody authorized for severe COVID-19 treatment in hospitalized patients.
Key facts at a glance
- RxNorm
- 2639632
- Generic
- Gohibic
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Authorized for emergency use in hospitalized adults with severe COVID-19 pneumonia who require supplemental oxygen, invasive mechanical ventilation, or extracorporeal membrane oxygenation (ECMO). Note: Specific clinical indications may have changed since my knowledge cutoff.
Gohibic is a monoclonal antibody that specifically binds to and inhibits C5a, a key complement protein involved in inflammatory responses. By blocking C5a, it reduces excessive inflammatory activation that can damage tissues in severe COVID-19.
Administered as an intravenous infusion. Common adverse effects include pneumonia, sepsis, and other infections. Should only be used in hospitalized settings under healthcare provider supervision. Effectiveness and safety information may be limited or have been updated since my knowledge cutoff; consult current prescribing information for the most accurate details.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy