Granisetron
Granisol is a brand-name antiemetic medication containing granisetron, a 5-HT3 receptor antagonist. It is primarily used to prevent acute nausea and vomiting associated with chemotherapy, radiation therapy, and surgical procedures. This medication works by blocking serotonin signals in the brain and gastrointestinal tract that trigger the vomiting reflex.
Granisol is used to prevent chemotherapy-induced and post-operative nausea and vomiting by blocking serotonin receptors.
Key facts at a glance
- RxNorm
- 763504
- Generic
- Granisol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of acute nausea and vomiting associated with chemotherapy (particularly cisplatin-based regimens), radiation therapy, and surgery. May be used for both adult and pediatric patients depending on the specific formulation and indication.
Granisetron is a selective 5-hydroxytryptamine-3 (5-HT3) receptor antagonist. It works by blocking serotonin from binding to 5-HT3 receptors in the central nervous system (specifically in the chemoreceptor trigger zone) and in the gastrointestinal tract, thereby preventing the activation of the vomiting reflex.
Granisol is typically administered orally or intravenously. Common side effects may include headache, constipation, and diarrhea. As with all antiemetics, it is used prophylactically rather than for established nausea. Patients should inform their healthcare provider of all medications being taken due to potential interactions.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy