Gris-Peg
Gris-Peg is a prescription antifungal medication used to treat skin, hair, and nail infections caused by certain fungi, including ringworm and athlete's foot. It works by preventing fungal cells from dividing and spreading, allowing the body's immune system to eliminate the infection. Treatment typically requires several weeks to months, as the medication concentrates in keratin-containing tissues.
Gris-Peg is an oral antifungal used to treat fungal infections of the skin, hair, and nails.
Key facts at a glance
- RxNorm
- 203414
- Generic
- Gris-Peg
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Gris-Peg treats dermatophyte infections including tinea corporis (ringworm), tinea capitis (scalp ringworm), tinea pedis (athlete's foot), and tinea unguium (fungal nail infections). It is specifically effective against fungi that invade keratinous tissues.
Gris-Peg is an antifungal agent that binds to tubulin in fungal cells, disrupting the mitotic spindle and preventing cell division. It accumulates in keratin-rich tissues such as skin, hair, and nails, where it inhibits fungal growth and allows replacement of infected keratin.
Gris-Peg is taken orally with fatty meals to enhance absorption. Treatment duration ranges from 2-8 weeks for skin infections to several months for nail infections. Common side effects include headache, GI upset, and photosensitivity. It may cause liver toxicity and has significant drug interactions. Not effective against yeast infections or bacterial infections.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy