Nonoxynol-9
Gynol II is a non-prescription vaginal contraceptive product containing the spermicide nonoxynol-9. It is applied intravaginally before intercourse to help prevent pregnancy. This brand-name medication is available over-the-counter and may be used alone or with other contraceptive methods such as condoms or diaphragms.
Gynol II is an OTC vaginal spermicide used to help prevent pregnancy when applied before intercourse.
Key facts at a glance
- RxNorm
- 809438
- Generic
- Gynol Ii
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Gynol II is indicated for the prevention of pregnancy. It is a topical vaginal contraceptive intended for use by women of childbearing age. It may be used alone or in combination with barrier methods such as condoms or diaphragms for additional protection.
Gynol II contains nonoxynol-9, a surfactant-type spermicide that works by disrupting the cell membrane of sperm, causing them to become immobilized and unable to fertilize an egg. The product is placed deep in the vagina prior to intercourse to coat the cervical area.
Gynol II is less effective when used alone compared to hormonal or intrauterine contraceptives. It does not protect against sexually transmitted infections (STIs). Frequent use may cause vaginal or penile irritation and may increase the risk of urinary tract infections. For maximum effectiveness, it should be applied no more than one hour before intercourse and reapplied with each act of intercourse. Users should read all labeling carefully and consult a healthcare provider with any questions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy