Haemophilus Influenzae B Vaccine
This is a conjugate vaccine that protects against Haemophilus influenzae type b (Hib) bacteria, which can cause serious invasive infections including meningitis, pneumonia, epiglottitis, and sepsis. It is primarily used in infants and young children as part of routine childhood immunization schedules, with the protein conjugation enhancing immune response in young children who don't respond well to polysaccharide-only vaccines.
A conjugate vaccine for children that protects against serious Hib infections like meningitis by linking bacterial polysaccharides to a protein carrier to boost immunity.
Key facts at a glance
- RxNorm
- 798444
- Generic
- Haemophilus Influenzae B (Ross Strain) Capsular Polysaccharide Meningococcal Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Vaxelis, PedvaxHIB
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe, injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of Haemophilus influenzae type b (Hib) invasive diseases including meningitis, pneumonia, bacteremia, epiglottitis, and other serious infections in infants and young children. Typically administered as part of routine childhood vaccination schedules starting at 2-6 months of age.
The vaccine contains capsular polysaccharides from Hib bacteria conjugated (chemically linked) to a meningococcal protein carrier. This conjugation converts the T-cell independent polysaccharide antigen into a T-cell dependent antigen, enabling a stronger and more durable immune response, particularly in young children whose immune systems cannot effectively respond to polysaccharide antigens alone.
Contraindicated in individuals with severe allergic reactions to any vaccine component. May cause mild side effects such as redness, swelling at injection site, or fever. Not a substitute for meningococcal vaccines as it only protects against Hib, not Neisseria meningitidis. Complete the full vaccination series for optimal protection.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy