Haloprogin
Haloprogin is a topical antifungal medication that was used to treat superficial fungal infections of the skin, particularly dermatophyte infections such as tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm). It was applied directly to the affected skin area in cream or solution form and worked by disrupting fungal cell membrane function.
Topical antifungal medication formerly used to treat superficial skin fungal infections like athlete's foot and ringworm.
Key facts at a glance
- ATC
- D01AE11
- RxNorm
- 26422
- Generic
- Haloprogin
- Class
- atc-d01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- cream, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteravoid if possible
use only if benefits outweigh potential risks, topical application preferred over systemic
regular prenatal checkups
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse lowest effective dose
topical application only, avoid large body surface area coverage
standard prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse with caution
topical use acceptable, avoid near time of delivery if possible
routine prenatal care
Use with caution and monitor for adverse effects.
lactation
nursing mothersavoid applying to breast area
wash hands thoroughly before nursing, do not apply to breasts
observe infant for skin reactions
Use with caution and monitor for adverse effects.
pediatric_age
children under 12use as directed, adult strength typically safe
supervise application, avoid ingestion
monitor for skin irritation
geriatric
elderlyno adjustment needed
standard dosing applies, monitor for skin sensitivity
check for irritation or allergic reaction
renal_impairment
mild to moderateno adjustment needed
topical use with minimal systemic absorption makes this safe
standard monitoring
hepatic_impairment
anyno adjustment needed
minimal systemic absorption makes hepatic metabolism irrelevant
standard care
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class
Drug class information
Common uses
Common therapeutic uses
Route of administration
Administration route information
Haloprogin was indicated for the treatment of superficial dermatophyte infections including tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea manuum. It was used for fungal infections caused by Trichophyton, Microsporum, and Epidermophyton species.
Haloprogin is an aryliodonium compound with antifungal activity. It exerts its effect by disrupting fungal cell membrane function, leading to cell death. As a topical agent, it penetrates the outer layers of skin to reach the site of fungal infection.
Haloprogin has been discontinued and is no longer available in many countries, including the United States. Patients should consult current antifungal alternatives such as clotrimazole, miconazole, terbinafine, or ketoconazole. As a topical preparation, systemic absorption was minimal, though skin irritation or allergic reactions could occur. Always follow prescribing information and consult a healthcare provider for appropriate diagnosis and treatment of fungal skin infections.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy