Carboprost
Hemabate (carboprost tromethamine) is a synthetic prostaglandin F2α analogue used primarily in obstetrics to manage postpartum hemorrhage when conventional methods are ineffective. It acts as a uterotonic agent, causing sustained uterine contractions that help control excessive bleeding after childbirth.
Hemabate is a prostaglandin-based injection used to control postpartum bleeding by stimulating uterine contractions.
Key facts at a glance
- RxNorm
- 50808
- Generic
- Hemabate
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of postpartum hemorrhage unresponsive to conventional therapies, second-trimester pregnancy termination (intrauterine fetal death or congenital anomalies), and refractory spontaneous abortion.
As a prostaglandin F2α analogue, Hemabate binds to prostaglandin receptors in the uterine muscle, stimulating sustained myometrial contractions that compress bleeding vessels at the placental site and promote hemostasis.
Administered via deep intramuscular injection. Contraindicated in patients with active pelvic inflammatory disease, asthma, or hypersensitivity to prostaglandins. Common side effects include fever, chills, nausea, vomiting, diarrhea, and flushing. Requires clinical monitoring during administration.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy