Hyaluronate
Hyaluronate is a naturally occurring polysaccharide that serves as a lubricating and cushioning agent in the body. It is administered via injection into joints for osteoarthritis, applied topically to the eyes for dry eye symptoms, or used as a viscoelastic solution during ophthalmic surgery to protect delicate tissues.
Hyaluronate is a lubricating substance used to treat joint pain, dry eyes, and protect tissues during eye surgery.
Key facts at a glance
- ATC
- unclassified
- RxNorm
- unknown
- Generic
- Hyaluronate
- Class
- unclassified
- Brands
- Gel-One, IPM Wound, Nexha, Monovisc, Hyalgan, Genvisc, Gel-Syn, Visco-3, Amvisc, Healon, Biolon, Trivisc, Durolane, Hymovis, Provisc
- Availability
- otc
- Pregnancy
- B
- Lactation
- safe
- Half-life (h)
- 0
- Onset (min)
- 0
- Duration (h)
- 0
- Routes
- oral, topical, ophthalmic
- Forms
- injection, topical gel, ophthalmic solution, oral capsule
- Regions
- United States, Europe, Canada, Australia, Japan
- Monitoring
- allergic reactions, injection site reactions, ocular complications, skin irritation
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for symptomatic relief of osteoarthritis (especially knee osteoarthritis) via joint injection, treatment of dry eye syndrome via topical drops, and as a viscoelastic surgical aid during ophthalmic procedures such as cataract surgery.
Acts as a viscous supplement to replace or augment the body's natural hyaluronic acid, providing lubrication, shock absorption in joints, and protective coating for sensitive tissues during surgery.
Generally well-tolerated but may cause temporary injection site pain when used for joints. Rare allergic reactions can occur. Not recommended for use in infected joints or during active skin inflammation. Patients should follow their healthcare provider's specific administration schedule, typically given as a series of injections.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy