Topotecan
Hycamtin (topotecan) is a prescription chemotherapy medication used to treat certain types of cancer, including small cell lung cancer and ovarian cancer. It belongs to a class of drugs called topoisomerase I inhibitors, which work by interfering with cancer cell division and growth. This medication is typically used when other cancer treatments have not been effective.
Hycamtin is a chemotherapy drug used to treat certain cancers by inhibiting cancer cell division.
Key facts at a glance
- RxNorm
- 203472
- Generic
- Hycamtin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Hycamtin is FDA-approved for the treatment of small cell lung cancer and ovarian cancer. It may also be used for other cancers as determined by an oncologist, particularly in cases where initial treatments have not worked or the cancer has returned.
Hycamtin is a topoisomerase I inhibitor. It works by blocking an enzyme called topoisomerase I, which is essential for cancer cell division. By inhibiting this enzyme, the medication prevents cancer cells from replicating their DNA, ultimately leading to cell death.
Hycamtin is administered intravenously by a healthcare professional and requires careful monitoring. Common side effects include low blood cell counts, nausea, fatigue, and hair loss. It should only be used under the supervision of an oncologist experienced with chemotherapy. Patients should discuss all current medications and health conditions with their doctor before starting treatment.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy